Scripps Research scientists have found that LY2444296 - a compound that selectively blocks the kappa opioid receptor (KOP) - may reduce drinking in cases of alcohol dependence in animal studies. The ...

A new compound tested at the Miguel Hernández University of Elche (UMH) in Spain shows promising effects in reducing alcohol consumption and motivation to drink in mice, with marked sex-dependent ...

The other compound is PF-4575180. Both were developed by Pfizer. "Alcohol and nicotine addiction are often treated as separate disorders," Bartlett says, "despite the fact that 60 to 80 percent of ...

The 2019 National Survey on Drug Use and Health reported that 14.5 million people ages 12 and older have alcohol use disorder, or AUD. This represents 5.3% of that population, according to the ...

Modern mental health company Clerkenwell Health announced today that it is working with clinical-stage biotechnology company Beckley Psytech on a Phase IIa study investigating whether a novel ...

Psilocybin—the active ingredient in so-called psychedelic or magic mushrooms—given in combination with psychotherapy curbed drinking in adults with alcohol use disorder for at least eight months, ...

Given that alcohol is the most frequent functional group found in bioactive natural products and marketed drugs, and is a versatile synthetic intermediate with a middle level of carbon oxidation state ...