Director, Biomedical and Health Innovation, The University of Western Australia and WA Life Sciences Innovation Hub; President, Australasian Society of Clinical and Experimental Pharmacologists and ...

Receptor tyrosine kinases (RTKs) regulate many critical biological processes such as cell growth, differentiation, and survival through the recruitment of intracellular signaling molecules. The ...

Cell surface receptors, such as the G-protein coupled receptor (GPCR) and receptor tyrosine kinase (RTK), play central roles signalling pathways. Due to their central role in regulating a wide range ...

A dream drug would provide a targeted therapeutic effect without side effects. Biased signalling, whereby certain cellular signalling pathways are favoured over others, could make this a reality. Now, ...