Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...
The field of cancer immunology has witnessed dramatic progress with the advent of immunotherapies targeting the tumor immune microenvironment (TIME).
The researchers used lipid nanoparticles (LNPs) to deliver cyclic GMP-AMP (cGAMP) synthase (cGAS) mRNA to cancer cells. This results in production of the endogenous stimulator of interferon genes ...
Gastric cancer cells can activate KRAS-driven signals, enabling autonomous tumor growth by producing their own WNT proteins. New research reveals how gastric cancer cells exploit WNT signaling for ...
Understanding why cancer cells rely on specific genes is critical for designing effective targeted therapies. A new study ...
From the deep sea to the shallow seafloor, researchers are uncovering unusual sugars that do something extraordinary to ...
Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by ...
A study led by researchers at Moffitt Cancer Center found that normal cells surrounding a tumor, known as cancer-associated ...
A protein once thought to simply help cancer cells avoid death turns out to do much more. MCL1 actively drives cancer ...
Cell-based immunotherapies have transformed cancer treatment, yet their widespread use remains constrained by safety risks, ...