(A) Histone staining images and OI-DIC density imaging of human living cells in the interphase (the phase between cell divisions, left) and mitotic phase (right). The bottom two rows are OI-DIC ...

The use of high-resolution bright-field microscopy is essential for cellular-scale biological research, but this technique has limitations due to low image contrast. Using dyes on the sample can ...

The ability to achieve spatial resolutions that are greater than is possible in standard optical microscopy is what makes electron microscopy so important for the investigation of nanoscale structures ...