DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

Scientists from the RNA Institute at the University of Albany (UAlbany) have developed new methods for designing and assembling DNA nanostructures that enhance their potential for use in various ...

“Our lab is generally interested in discovering and characterizing previously unknown or poorly understood factors that are essential for genome maintenance. This is particularly important in the ...

Researchers explore a basic building block used in the fabrication of many DNA nanoforms. Known as a Holliday junction, this nexus of two segments of double stranded DNA has been used to form ...