Vaccine constructs utilizing the mammalian expression system pSecTag2b were prepared as naked plasmid in 1xPBS, as described in previous publications 10. The vaccine construct comprised of Eα peptide ...
Engineered immunosuppressive and fibrosis-targeted dendritic cells expressing a chimeric antigen receptor (CAR)-like construct (iCDCs) protect against pathological cardiac remodelling in animal models ...
EPFL researchers have successfully engineered cells of the immune system to more effectively recognize cancer cells. The work, covered in two papers, turns the previously lab-based method into a ...
The immune system consists of inflammatory and regulatory T cells (Tregs) that promote or dampen immune activity, respectively. These cells react to specific antigens that specialized cells like ...
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