High-concentration injectable formulations present unique challenges. Poor solubility issues are often associated with small-molecule APIs formulated for oral administration. Solubility is also ...

Pharmaceutical Technology brought together a panel of industry experts for a special forum to discuss solubilizing polymers and the related formulation strategies for ...

For drug compounds trying to make their way from the lab to the market, poor solubility is often the kiss of death. It’s one of the most common reasons for a drug candidate to drop out of the ...

Despite the importance of predicting solubility, it is not an easy matter. One approach, using 'brute force' simulations, requires long computing times. Other techniques, while faster, fail to predict ...