Again, the FDA does not regulate dietary or weight loss supplements, including weight loss patches. As a result, adverse side effects such as nausea, headache, increased heart rate (a.k.a tachycardia), and skin irritation near the application site are possible, says Dr. Peralta-Reich.

Oprah Winfrey has lost 26 pounds since 2015 through programs like Weight Watchers and GLP-1 weight loss medications. Here's everything to know about Oprah Winfrey's weight loss journey.

Changes are coming in 2026 for GLP-1 drugs. Long defined by high prices, shortages and weekly injections, drugs including Wegovy and Zepbound are expected to be easier to access and afford. And new options for people averse to needles are coming.

The National Institute for Health and Care Excellence (Nice), England’s drug approval body, states that adults qualify for treatments such as Mounjaro and Wegovy if they are obese with a body mass index (BMI) of at least 35 and have at least one pre-existing weight-related health conditions.

Jelly Roll is crediting his weight loss for improving his sex life with wife Bunnie Xo. “My testosterone level — and I’m cool to talk about this openly — was of a preteen boy,” the country singer, 41,

Celebrities have embraced GLP-1 medications for dramatic weight loss in 2025. Oprah Winfrey, Amy Schumer, Meghan Trainor and Lizzo share their health journeys.