Lamellipodia are veil-shaped protrusions of the plasma membrane, that can turn into upward-curled ruffles if they fail to adhere to the substrate. A dendritic meshwork of short and highly branched ...

Cell migration occurs normally during embryonic development, the immune response and wound healing, but also under pathological conditions, like cancer dissemination. Therefore, understanding the ...

Some of the body's cells stay put for life, while others are free to roam. To move, these migratory cells rely on filopodia—sensitive, finger-like protrusions that reach out from the cell membrane ...

Superresolution microscopy offers the advantage of imaging biological structures within cells at the nano-scale. Here we apply two superresolution microscopy techniques, specifically 3D structured ...

Lamellipodia and filopodia are dynamic surface extensions of the cell which play a pivotal role in cell migration, invasion and wound healing. Biochemists have succeeded in clarifying the interplay ...