Discriminating different immune cell types is typically done by flow cytometry and fluorescence-activated cell sorting (FACS), which can identify distinct populations of cells according to their size, ...

Researchers from Tokyo Medical and Dental University (TMDU), collaborating with scientists from the Marine Biological Laboratory (MBL) and RIKEN, develop a novel technique for live-cell fluorescent ...

As a result, the building block is removed from the fluorescent dye and its fluorescence is switched "on". The probe selectively and sensitively indicates the presence of serotonin, even inside cells.

Cell membrane coated biomimetic nanoparticles (NPs) have been widely studied in nanomedicine because of their unique properties such as immune escaping, long blood circulation, specific molecular ...

The folding state of the proteins in live cells often reflect the cell's general health. Scientists have developed a molecular probe that senses the state of the proteome -- the entire set of the ...

Scientists monitor dynamic cellular events in real time with live cell imaging and detection techniques. A variety of approaches allow researchers to capture events missed by traditional methods that ...

Striking the Right Balance between Signal Strength and Long-Term Cell Health A key challenge with live-cell fluorescence imaging is the ability to visualize weak fluorescent signals over background ...

Imagine an orchestra composed of 100 musicians, all playing a different instrument. Now consider what you'd hear if all of the musicians began playing a symphony, but with each starting on a different ...

A fluorescent probe for visualizing the signaling dynamics in metastatic cancer cells has been developed. A research team at the University of Turku (Finland), led by Johanna Ivaska and James Conway, ...

The probes consist of two fluorescent dyes that render each other invisible when they're tethered together with the antibody as part of the delivery system. When the linker breaks and untethers the ...