The hepatic immune landscape is a dynamic compartment, notably composed of highly heterogeneous and adapting myeloid cells. Liver resident macrophage distribution across the tissue and bone-marrow ...

Autoimmune liver diseases (ALDs), including autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and primary sclerosing cholangitis (PSC), are complex conditions involving the liver's immune ...

A study led by clinician-scientists and scientists from the National Cancer Centre Singapore (NCCS) and A*STAR's Genome Institute of Singapore (GIS) and funded by the National Research Foundation ...

This review manuscript highlights the relevance of spatially-resolved macrophage phenotyping in liver disease-related research. The liver is a vital organ heavily populated with macrophages, which ...

Hepatoblasts differentiate into hepatocytes, large and small cholangiocytes. CK8, CK18, and CK19 are expressed in hepatoblasts. CK8 and CK18 are expressed in hepatocytes at week 6. CK19 is expressed ...