Researchers at the University of Maryland School of Medicine have discovered that calcium channel blockers--widely used to treat heart problems and high blood pressure--work differently than ...

When you have atrial fibrillation, the two upper chambers of your heart (atria) don't beat in sync with the two lower chambers (ventricles). This makes your heart beat out of rhythm and sometimes very ...

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

Myotonic dystrophy is one of the most common forms of muscular dystrophy. It is a genetic condition that causes progressive muscle weakness and wasting. No treatments currently exist that slow the ...

UNIVERSITY PARK, Pa. -- L-type calcium channel blockers (LCCBs) -- the most widely used drugs for treating hypertension -- may harm the heart as much as help it, according to a new study. The research ...

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

Large-conductance calcium-activated potassium (BK) channels are critical determinants of smooth muscle function by mediating rapid feedback between intracellular calcium levels and membrane potential.

Little additional work has been performed beyond that of Lee et al. [1,3,10] to further investigate the proposed dual action of ibutilide. Our laboratory has sought to examine the effects of sodium ...

Irregular heartbeat conditions affect millions of people worldwide, causing hearts to beat too fast, too slow, or with an uneven rhythm. These cardiac rhythm disturbances, medically known as ...