The innate immune system serves as the body's first line of defence, rapidly detecting and responding to external pathogens and internal damage. Recent advances in the field have highlighted the ...

Innate immunity constitutes the body’s first line of defence against invading pathogens. This ancient, evolutionarily conserved system is activated within minutes of encountering foreign agents, ...

The interferon regulatory factor (IRF) family of transcription factors, pivotal for initiating antiviral type I interferon ...

Published on January 6, 2026, in Volume 2 of the Immunity & Inflammation journal, the review begins by underscoring Professor Taniguchi's ...

Researchers have deciphered the complex interplay of various enzymes around the innate immune receptor toll-like receptor 7 (TLR7), which plays an important role in defending our bodies against ...

Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation ...

A sugar on mycobacteria binds to the immune receptor dectin-1 on host macrophages, helping the bacteria survive and driving ...

Before invaders can be stopped, they must first be detected, and this is accomplished by pattern recognition receptors located on the surface of plant cells. The ability of these receptors to detect ...

Plants are continuously evolving new immune receptors to ever-changing pathogens. Researchers at the RIKEN Center for Sustainable Resource Science (CSRS) have traced the origin and evolutionary ...