Editor's note: Citation Classics Commentaries were written by the authors of studies that were some of the most highly cited papers between 1961 and 1975. The essays were originally published between ...

Electron microscope (EM) has revolutionized our ability to visualize the intricate details inside cells. The advancement to 3D electron microscopy, known as volume EM (vEM), has further expanded this ...

Researchers have combined two microscopic imaging techniques in one microscope, providing scientists with a high-resolution method of tracking single molecules in a cellular context. The development ...

Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...

Cryo-electron microscopy has exposed the structure of a bacterial virus with unprecedented detail. This is the first structure of a virus able to infect Staphylococcus epidermidis, and high-resolution ...

Analysis of the nanomaterials and the effect of the liquid environment on them is interesting for understanding their fundamental properties, which is possible through liquid cells. Synthesis of ...

In transmission electron microscopy (TEM), where the electron beam passes through the sample to be directly imaged on the detector below, it is often necessary to support the thin samples on a grid.