(SALT LAKE CITY)—A new study by researchers at the University of Utah School of Medicine sheds light on a longstanding question about the role of mitochondria in debilitating and fatal motor neuron ...

You may already be familiar with ALS, especially if you took part in the viral ice bucket challenge to raise awareness of the ...

Treatment with Evrysdi (risdiplam) may modestly improve arm function for adults with spinal muscular atrophy (SMA), a new study indicates.

Adopting some of the strategies behind successfully treating the childhood disease spinal muscular atrophy may enable development of therapies to curb the muscle decline that accompanies aging, new ...

A new McGill University study has found a direct link between age-related declines in neuron activity in the cerebellum and ...

Motor neurons are some of the largest cells in the human body. In particular, upper neurons—extending from the cerebral cortex to the brain stem or spinal cord—average 60μm in diameter. 3,4 These ...

As people grow older, many notice that their balance is not as steady as it used to be. Walking may become slower, climbing ...

Primary lateral sclerosis (PLS) and amyotrophic lateral sclerosis (ALS) are neurodegenerative diseases. PLS typically develops slowly, while ALS rapidly affects mobility and can become fatal.

By examining mice across the lifespan, researchers showed that age lowers firing rates in cerebellar Purkinje cells, leading to poorer motor coordination. Reversing this decline improved performance, ...