Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

As a fast and easy-to-use gene-editing technique, CRISPR is one of the biggest discoveries in 21 st century medical science, and an important facilitator of gene therapy development. Several gene ...

Inflammation has to fight pathogens fast—but it can't get out of control. Researchers at the German Cancer Research Center ...

Gene therapy currently represents the most promising approach for the treatment of hereditary diseases. Yet despite significant breakthroughs in recent years, there are still a number of hurdles that ...

A new CRISPR breakthrough shows scientists can turn genes back on without cutting DNA, by removing chemical tags that act ...

The great hope for gene therapy is that one day it will be out of the clinic and into mainstream therapeutics. Bearing enormous potential to treat or cure disease, such technology can replace a ...

The development of gene editing tools, which enable the specific targeting and correction of mutations, hold the promise of allowing us to correct those mutations that cause genetic diseases. However, ...

A patient death in a CRISPR trial halts gene editing studies, raising critical safety questions. What this means for the ...

The energy factories in our cells contain their own genes, and genetic mutations in them can cause deadly inherited diseases. These oblong-shaped organelles, or mitochondria, translate genes into ...

Artificial intelligence (AI) is known for enabling deeper insights into drug development, identifying patterns and molecules that may otherwise go unnoticed. Now it is poised to make similar ...