Misfolded proteins can appear as small aggregates, soluble monomers, or large insoluble inclusion bodies. While the fundamental biophysical mechanisms that cause cytotoxicity are not fully understood, ...
Protein folding raises some of biology's greatest theoretical challenges. It also lies at the root of many diseases. For example, the fundamental question of whether a protein's final tertiary ...
The latest short science news items from C&EN. Proteins are vital for life, involved in virtually every biochemical process that makes life possible. They comprise one or more amino acid chains ...
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The sensory receptor PIEZO1 changes shape in response to mechanical stimuli. The super high-resolution microscopy technology used in this discovery is a breakthrough in enabling protein structures to ...
Hanwen Zhu, PhD, left, and Ji Sun, PhD, center, of the Dept. of Structural Biology, and Martin Turk, PhD, right, of the Cryo-Electron Microscopy Center discuss the structure of the active form of ...
Every cell depends on proteins to function and stay healthy. These proteins are made inside the cell from amino acids, but ...