On the left is integrase in its “intasome” structure of four identical four-part complexes (pink) that connect to create one 16-part complex that locks around viral DNA (blue). On the right is ...
Expert Rev Proteomics. 2008;5(3):507-528. Although it is widely known that HIV-1 initiates a profound global host cell response to infection, it is difficult to trace specific expression and pathway ...
IRVINE, Calif., Monday, April 18, 2005 – The increased frequency of drug resistance in isolates of the AIDS virus, HIV, makes identification of new antiviral targets an urgent necessity. Host genes ...
Researchers at Johns Hopkins Medicine, in collaboration with researchers at the National Institutes of Health, report that two new studies in mice with a humanized immune system and human cell lines ...
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