In a serendipitous discovery, UC San Diego researchers using cryo-EM technology captured the first visualizations of the 3-D structure of the muscle acetylcholine receptor in fetal and adult muscles.

“This article illuminates the biology behind EDG-5506, demonstrating that modulation of fast skeletal muscle contraction protects against muscle injury, degeneration and fibrosis in models of DMD,” ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Scientists have developed a specially formulated bioink, which contains microparticles engineered for sustained delivery of insulin-like growth factor-1 (IGF-1). This delivery enhances the formation ...

- Muscle cells, also known as myocytes, are specialized cells designed for contraction and force production. Skeletal Muscle Cells: These cells are long, cylindrical, and have a striated (or striped) ...

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...

Researchers have identified a protein that’s critical to the development of skeletal muscle mass and strength and the tissue’s ability to metabolize glucose. They say their findings may lead to ...

Skeletal muscle is the type of muscle that controls movement. Problems with these muscles can be minor, life-threatening, or ongoing problems that make it hard to perform basic daily activities.

Using powerful new visualization technologies, researchers have captured the first 3-D images of the structure of a key muscle receptor, providing new insights on how muscles develop across the animal ...