When formulating mRNA into lipid nanoparticles (LNP), various copy numbers of mRNA are encapsulated, leading to a distribution of mRNA loading levels within the LNPs. It is unclear whether the mRNA ...

A Few Key Considerations Are Essential to Obtain the Best Return from Cell-Based Experiments Because optimal DNA delivery into mammalian cells depends on multiple factors, we recommend optimizing ...

Transfection is a crucial non-viral technique for introducing DNA or RNA into cells, yet achieving high efficiency and consistency can be challenging, particularly with difficult cell types.

Developers are increasingly exploring non-viral gene delivery methods as safety issues with viral vectors draw scrutiny. Advances in lipid nanoparticles, polymer carriers, and electro-transfection are ...

In this interview, News Med talks to Hinnah Campwala about the pivotal role of transfection in modern research and drug discovery. Transfection is a tool that sees widespread use across a diverse ...

Lack of Straightforward Solution for Gene Transfer Hampers Growth in This Sector Transfection of nucleic acids into cells is often cited as users’ rate-limiting step in numerous biomedical research ...

Developers are increasingly exploring non-viral gene therapy delivery methods as safety concerns over viral vectors grow. Approaches such as lipid nanoparticles, Sleeping Beauty transposons, and ...