Konstanz researchers identify an enzyme that plays a role in the migration of cells in our body—not only during normal tissue formation and wound healing, but also when tumor cells metastasize. This ...

Every cell in the body normally has its fixed place as part of a tissue structure. Except for a few cell types, such as blood or immune cells. But cancer cells also cross established boundaries, grow ...

Cancer cells that accumulate extra copies of their entire chromosome set can start behaving like immune cells, swallowing ...

Cancer cells can disarm the immune system not just by hiding from it, but by actively reprogramming nearby immune cells into a suppressed state. This previously unrecognized molecular interaction, ...

Ikoma, Japan—Ever wondered how the different cells in our body communicate with each other to fulfill their different roles—be it cells repairing a tissue injury or immune cells moving towards an ...

Tumor-associated calcium signal transducer 2 (TROP2) is a transmembrane glycoprotein involved in different signaling pathways that promote proliferation, migration and invasion of tumoral cells, and ...

Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related condition associated with increased mortality among patients with cancer. CHIP mutations with high variant-allele frequencies ...

Triple-negative breast cancer (TNBC) is the subtype of breast cancer that is the hardest to treat. TNBC patients account for more than 20,000 cases of this condition annually in the U.S. alone. They ...

Understanding which cells within a tumor will go on to form metastases remains one of the major challenges in cancer research ...

This article and associated images are based on a poster originally authored by W. Strijker, I. Voskamp, B. Duggan, L. de Haan, W. Celus, and L. Gijzen and presented at ELRIG Drug Discovery 2025 in ...