Mayo Clinic researchers have identified how excessive alcohol use can drive the development of fatty liver disease. The culprit is a disruption of a protein-recycling enzyme (VCP), which normally ...
Healthy cells are constantly breaking down proteins and building up new ones with the help of enzymes aptly named unfoldases, because they unravel proteins tagged for destruction or recycling. Now, a ...
If the enzyme p97/VCP works properly, the cell is able to break down accumulations of misfolded proteins. They can be seen in the left image as white dots inside the cell. After blocking the enzyme, ...
Mayo Clinic researchers have pinpointed how excessive alcohol consumption contributes to fatty liver disease, a condition that affects more than one in three people in the U.S. Also known as Metabolic ...
(MEMPHIS, Tenn. – October 8, 2025) Stress granules are droplet-like protein hubs that temporarily shield fragile RNA from cellular stresses such as toxins. VCP is a protein essential for breaking up ...
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Excessive alcohol affects a protein-recycling enzyme, which can lead to fatty liver disease
Mayo Clinic researchers have pinpointed how excessive alcohol consumption contributes to fatty liver disease, a condition that affects more than one in three people in the U.S. Subscribe to our ...
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