Researchers at Cincinnati Children's Hospital Medical Center in collaboration with Roche, have developed a next-generation human liver organoid microarray platform that could help predict which drugs ...

The central vein (CV) region, driven by the Wnt signaling pathway, and the portal vein (PV) region, driven by the Notch signaling pathway, enable us to construct a biomimetic liver lobule ...

Organoids are small-scale models that mimic human organs. These models could help scientists understand diseases and test treatments, and potentially aid in regenerative therapeutic methods. Organoids ...

Scientists from Cincinnati Children's and colleagues based in Japan report achieving a major step forward in organoid technology: producing liver tissue that grows its own internal blood vessels.

Researchers in South Korea have developed an organoid disease model and non-destructive stiffness analysis technology for evaluating the efficacy of new drugs for fatty liver disease. The research ...

A novel 3D cell culture method has been developed that encourages liver progenitor cells to self-organize and form blood vessel networks for the first time. The development of accurate liver organoids ...