Myc - Wikipedia
The Myc family consists of three related human genes: c-myc (MYC), l-myc (MYCL), and n-myc (MYCN). c-myc (also sometimes referred to as MYC) was the first gene to be discovered in this …
MYC: there is more to it than cancer - PMC
MYC is a pleiotropic transcription factor involved in multiple cellular processes. While its mechanism of action and targets are not completely elucidated, it has a fundamental role in cellular proliferation, …
MYC Gene - GeneCards | MYC Protein | MYC Antibody
Jan 15, 2026 · MYC (MYC Proto-Oncogene, BHLH Transcription Factor) is a Protein Coding gene. Diseases associated with MYC include Burkitt Lymphoma and High-Grade B-Cell Lymphoma Double …
MYC in cancer: from undruggable target to clinical trials
Feb 19, 2025 · This Review provides an overview of the various strategies to inhibit MYC, focusing on the most recently described inhibitors and those that have reached clinical trials.
MYC: a complex problem: Trends in Cell Biology
As an oncogenic driver, MYC amplifies global transcription by driving pause release and the early transcription, especially of highly expressed genes. It stimulates replication by facilitating assembly of …
MYC function and regulation in physiological perspective
Oct 24, 2023 · MYC interacts with several cofactors, chromatin modifiers, and regulators to direct gene expression. MYC levels are tightly regulated, and deregulation of MYC has been associated with …
MYC: Master Regulator of Cell Death and Tumor Progression
Mar 14, 2025 · MYC gene has become one of the most investigated oncogenes for regulating programmed cell death and tumor growth. MYC is a transcription factor that regulates the expression …
MYC: a multipurpose oncogene with prognostic and therapeutic ...
Aug 9, 2021 · In this review, MYC regulation and the mechanisms by which MYC adjusts cellular functions and its implication in hematologic malignancies are summarized. Further, we also discuss …
MYC gene's dual role in cancer growth and immune suppression - MSN
The cancer gene MYC camouflages tumors by suppressing alarm signals that normally activate the immune system.
MYC controls STING levels to downregulate inflammatory signaling in ...
Oct 11, 2024 · Amplification of the MYC proto-oncogene is frequently observed in various cancer types, including triple-negative breast cancer (TNBC). Emerging evidence suggests that suppression of …